Not sure that I've seen many people utilize these for off road purposes. Our trucks already have small cubby spaces built into the bed, so the swing case would just provide some extra storage there. We also have some under the seat storage in our trucks.
Pros: obviously, you'll get extra locations for storage and access to things inside the bed. I'm sure it's lockable as well.
Cons: probably provides limited access to the built in storage since you'll have to swing it out before access, limits access to the AC plug in the back of the truck. I would also imagine that these stick out taking up some bed space that you might want to utilize for a cooler, pull out fridge and extra gear in the bed of the truck.
What did you have in mind for going that direction?